Transcriptomic classification of prolactinomas and somatotropinomas identifies subtypes with variable resistance to treatment
Prolactinomas and somatotropinomas were classified into distinct transcriptomic groups. Resistance to medical therapies was linked to distinct tumor subtypes, suggesting distinct mechanisms of resistance.
Authors
- Karine Perlemoine
- Jerome Yves Bertherat (ORCID: https://orcid.org/0000-0003-2551-3008)
- Fidéline Bonnet-Serrano (ORCID: https://orcid.org/0000-0002-6628-8807)
- Bertrand Baussart (ORCID: https://orcid.org/0000-0003-0735-8278)
- Guillaume Assié (ORCID: https://orcid.org/0000-0001-9590-0906)
- Nesrine Benanteur (ORCID: https://orcid.org/0009-0008-2758-5500)
- Anne Jouinot
- Muriel Lombard
- Mirella Hage (ORCID: https://orcid.org/0000-0002-7458-7102)
- Chiara Villa (ORCID: https://orcid.org/0000-0001-6245-4487)
- Franck Letourneur (ORCID: https://orcid.org/0000-0001-9465-4774)
- Victor Gravrand
- Yoann Martin
- Fabio Bioletto (ORCID: https://orcid.org/0000-0001-7550-7023)
- Maria Francesca Birtolo (ORCID: https://orcid.org/0000-0001-8100-8394)
- Jean-François Emile
- Marie-Laure Raffin-Sanson
Institutions
- Centre National de la Recherche Scientifique (FR)
- Humanitas University (IT)
- Inserm (FR)
- Université de Versailles Saint-Quentin-en-Yvelines (FR)
- Université Paris Cité (FR)
- Hôpital Cochin (FR)
- Assistance Publique – Hôpitaux de Paris (FR)
- Community Care (US)
- Hôpital Lariboisière (FR)
- Department of Medical Sciences (BY)
- Hôpital Ambroise-Paré (FR)
- Institut Cochin (FR)
Publication Details
- Journal
- European Journal of Endocrinology
- Published
- 2025-09-30
- DOI
- https://doi.org/10.1093/ejendo/lvaf196
- Citations
- 1
- Primary Topic
- Pituitary Gland Disorders and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 1.29