Low skeletal muscle index combined with reduced bone density increases mortality rate in older adults with heart failure
The coexistence of reduced skeletal muscle mass and bone density synergistically increases mortality risk in older adults with HF. Early identification of musculoskeletal deficits through CT-based assessments may facilitate targeted interventions to reduce adverse outcomes. Integrated strategies addressing both bone and muscle loss are essential for improving long-term prognosis in this vulnerable population.
Authors
- Qinyue Wang
- S. Zhang (ORCID: https://orcid.org/0009-0006-1626-8732)
- Kailei Shi (ORCID: https://orcid.org/0009-0008-2885-8224)
- Xinkai Qu (ORCID: https://orcid.org/0000-0002-5000-6721)
- Yi‐Xiang Ye (ORCID: https://orcid.org/0000-0001-9066-334X)
- Huilin Che
- Mingxuan Li (ORCID: https://orcid.org/0000-0002-3987-4763)
- Junchao Yang (ORCID: https://orcid.org/0000-0003-4203-237X)
- Lin Qi
Institutions
- Shanghai Medical College of Fudan University (CN)
- Fudan University (CN)
- Huadong Hospital (CN)
- Obstetrics and Gynecology Hospital of Fudan University (CN)
Publication Details
- Journal
- Aging Clinical and Experimental Research
- Published
- 2025-10-28
- DOI
- https://doi.org/10.1007/s40520-025-03213-2
- Primary Topic
- Nutrition and Health in Aging
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Science and Technology Commission of Shanghai Municipality