A Multiomics Approach to Defining Target‐Organ Injury in Youths With Primary Hypertension: The SHIP AHOY Cohort
The integration of multiomics data in this unique pediatric population during the early phase of high BP provides evidence of molecular changes that reveal both potential drug targets and strategies for ameliorating BP-mediated cardiovascular target-organ injury.
Authors
- Kalyani Ananthamohan (ORCID: https://orcid.org/0000-0003-4794-9144)
- Mark Mitsnefes (ORCID: https://orcid.org/0000-0002-9904-0250)
- Lisa Joy Martin (ORCID: https://orcid.org/0000-0001-8702-9946)
- Bonita Falkner (ORCID: https://orcid.org/0000-0002-4242-4931)
- Sakthivel Sadayappan (ORCID: https://orcid.org/0000-0003-2006-7678)
- Richard C. Becker
- Michael J. Zilliox (ORCID: https://orcid.org/0000-0001-7381-8397)
- Julie R. Ingelfinger (ORCID: https://orcid.org/0000-0001-9039-2703)
- Coral D. Hanevold (ORCID: https://orcid.org/0000-0002-2795-1530)
- Qin M. Chen (ORCID: https://orcid.org/0000-0002-2409-7463)
- Marc B. Lande (ORCID: https://orcid.org/0000-0002-9467-5994)
- Stephen R. Daniels (ORCID: https://orcid.org/0000-0001-5520-6952)
- Joshua Samuels (ORCID: https://orcid.org/0000-0001-5682-4701)
- Michael A. Ferguson (ORCID: https://orcid.org/0000-0002-8751-3348)
- Kevin Meyers (ORCID: https://orcid.org/0000-0001-6653-269X)
- Tammy McLoughlin Brady (ORCID: https://orcid.org/0000-0002-1315-6747)
- Gina Kuffel (ORCID: https://orcid.org/0000-0003-4061-0092)
- Mohammed Arif (ORCID: https://orcid.org/0000-0001-5741-8860)
- Elaine M. Urbina
- Joseph T. Flynn
- Bernard Rosner
- Stephen R. Hooper
Institutions
- University of North Carolina at Chapel Hill (US)
- Boston Children's Hospital (US)
- Seattle Children's Hospital (US)
- Children's Hospital of Philadelphia (US)
- University of Arizona (US)
- Johns Hopkins University (US)
- Thomas Jefferson University (US)
- Loyola University Chicago (US)
- University of Washington (US)
- Johns Hopkins Medicine (US)
- Harvard University Press (US)
- University of Rochester Medical Center (US)
- Massachusetts General Hospital (US)
- Boston Children's Museum (US)
- University of Cincinnati Medical Center (US)
- University of Colorado Denver (US)
Publication Details
- Journal
- Journal of the American Heart Association
- Published
- 2025-10-28
- DOI
- https://doi.org/10.1161/jaha.124.037649
- Citations
- 1
- Primary Topic
- Cardiac Fibrosis and Remodeling
- Type
- article
- Field-Weighted Citation Impact
- 1.39