Differential metabolism of citalopram by 21 CYP3A4 variants: An in vitro experiment
This study provides the first systematic data on the impact of CYP3A4 variants on citalopram metabolism, suggesting that CYP3A4 genetic polymorphism plays a significant role in citalopram metabolism, and highlighting its potential value in individualized therapy.
Authors
- Xiaoxia Hu (ORCID: https://orcid.org/0000-0002-8807-5036)
- Junwei Li (ORCID: https://orcid.org/0000-0002-0727-7112)
- Peng Wang (ORCID: https://orcid.org/0000-0001-9325-359X)
Institutions
- Wenzhou Medical University (CN)
- Jinhua Central Hospital (CN)
Publication Details
- Journal
- Journal of Psychopharmacology
- Published
- 2025-10-28
- DOI
- https://doi.org/10.1177/02698811251375888
- Primary Topic
- Pharmacogenetics and Drug Metabolism
- Type
- article
- Field-Weighted Citation Impact
- 0.00