Management of Pediatric and Adolescent Rhabdomyosarcoma of the Chest Wall: An Expert Consensus Opinion From the International Soft Tissue Sarcoma Consortium (INSTRuCT)
The International Soft-Tissue Sarcoma Consortium (INSTRuCT) was established as a global partnership among various pediatric soft tissue sarcoma groups, including the Children's Oncology Group (COG), European Pediatric Soft Tissue Sarcoma Group (EpSSG), and Cooperative Weichteilsarkom Studiengruppe (CWS). One of INSTRuCT's primary objectives is to create consensus expert opinions for optimal clinical treatment. This consensus document provides evidence-based treatment recommendations for patients with rhabdomyosarcoma of the chest wall, including guidelines for staging, biopsy methods, local control strategies, radiation therapy, surgery timing, lymph node evaluation, reconstructive techniques, and long-term follow-up.
Authors
- Daniel S. Rhee (ORCID: https://orcid.org/0000-0003-1895-6679)
- Leo Y. Luo (ORCID: https://orcid.org/0000-0002-3061-4287)
- Ross Craigie (ORCID: https://orcid.org/0000-0002-3125-325X)
- Gabriela Guillén (ORCID: https://orcid.org/0000-0001-5632-2672)
- Andreas Schmidt (ORCID: https://orcid.org/0000-0001-9775-0403)
- Guido Seitz (ORCID: https://orcid.org/0000-0001-9280-1451)
- Timothy B. Lautz (ORCID: https://orcid.org/0000-0002-3323-6509)
- Jörg Fuchs (ORCID: https://orcid.org/0000-0001-6145-2391)
- Andre Cardoso Alemeida
Institutions
- Hebron University (PS)
- Lurie Children's Hospital (US)
- Johns Hopkins University (US)
- Universitätsklinikum Gießen und Marburg (DE)
- Johns Hopkins Medicine (US)
- Bristol Royal Hospital for Children (GB)
- University Children's Hospital Tübingen (DE)
- Vall d'Hebron Hospital Universitari (ES)
- Royal Manchester Children's Hospital (GB)
- Vanderbilt University Medical Center (US)
Publication Details
- Journal
- Pediatric Blood & Cancer
- Published
- 2025-10-27
- DOI
- https://doi.org/10.1002/pbc.32117
- Primary Topic
- Sarcoma Diagnosis and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Rally Foundation
- Maddie's Fund
- Strong
- Koning Boudewijnstichting