Small-scale external quality assessment of methylated <i>SHOX2</i> and <i>RASSF1A</i> detection in China: findings from 2023–2024
This two-round EQA study in China emphasizes the need for improvement in the performance of <i>mSHOX2</i> and <i>mRASSF1A</i> methylation detection. These results underscore the critical role of EQA schemes in monitoring and improving the detection quality in clinical laboratories. To address the challenges in <i>mSHOX2</i> and <i>mRASSF1A</i> detection, targeted recommendations are proposed to enhance detection accuracy and reliability.
Authors
- Xueliang Wang
- Ran Zhao (ORCID: https://orcid.org/0000-0003-3390-5343)
- Yingwei Chen (ORCID: https://orcid.org/0000-0001-8429-252X)
- Chengxiang Chu (ORCID: https://orcid.org/0000-0002-8560-5644)
- Xiaoyu Fan (ORCID: https://orcid.org/0000-0002-0390-5871)
- Xiaobo Sharon Hu (ORCID: https://orcid.org/0000-0002-6636-9738)
- Chunli Shi (ORCID: https://orcid.org/0000-0002-7373-3227)
Institutions
- Shanghai Academy of Science & Technology (CN)
- Shanghai Clinical Research Center (CN)
Publication Details
- Journal
- Clinical Chemistry and Laboratory Medicine (CCLM)
- Published
- 2025-10-28
- DOI
- https://doi.org/10.1515/cclm-2025-0846
- Primary Topic
- Epigenetics and DNA Methylation
- Type
- article
- Field-Weighted Citation Impact
- 0.00