Antiviral Potential of Brown Algal Metabolites Against A179L Anti-apoptotic Protein: A Computational Strategy for African Swine Fever Treatment
Five compounds (CID: 24796376, sargachromanol G, strictaepoxide, CID: 163107957, and saringosterone) with the strongest binding energies are recommended for in vitro and in vivo testing to validate their potential as therapeutic agents against ASFV.
Authors
- Mark Andrian B. Macalalad (ORCID: https://orcid.org/0000-0001-9613-3163)
- Fredmoore L. Orosco (ORCID: https://orcid.org/0000-0002-8861-7923)
Institutions
- University of Manila (PH)
- Department of Science and Technology (PH)
- University of the Philippines Manila (PH)
Publication Details
- Journal
- Current Topics in Medicinal Chemistry
- Published
- 2025-10-27
- DOI
- https://doi.org/10.2174/0115680266393922251005173927
- Primary Topic
- Animal Disease Management and Epidemiology
- Type
- article
- Field-Weighted Citation Impact
- 0.00