Molecular mechanisms of metformin action: From metabolic effects to lifespan extension and healthspan promotion
Metformin stands at the intersection of metabolic regulation and ageing biology. While not a panacea, its favourable safety profile and multi-targeted actions make it a leading candidate for repurposing as an anti-ageing therapy. Continued clinical validation is essential to translate these insights into practice.
Authors
- Svetlana Perović
- Stasa SCEPANOVIC
- Milan S. Vlaovic
- Aleksandra Filipović (ORCID: https://orcid.org/0000-0003-3578-5672)
- Slavica Vujović (ORCID: https://orcid.org/0000-0002-4024-9009)
Institutions
- University of Belgrade (RS)
- College of Nursing in Celje (SI)
- University Clinical Centre (PL)
- University of Montenegro (ME)
Publication Details
- Journal
- Journal of Medical Biochemistry
- Published
- 2025-10-28
- DOI
- https://doi.org/10.5937/jomb0-60849
- Primary Topic
- Metabolism, Diabetes, and Cancer
- Type
- article
- Field-Weighted Citation Impact
- 0.00