Trends and Disparities in Liver Cancer Incidence by Demographic Factors in the United States (1999-2020)

This study shows state-wise variations in liver cancer incidence; however, crude rates per 100,000 remain relatively consistent across states. Over 22 years, liver cancer rates have increased, with the highest incidence found in men, White individuals, and those aged 65-74. Incidence increased for individuals over 45, but by the end of two decades, rates for ages 45-54 decreased while remaining high for ages ≥55. A more prominent upward trajectory was observed in men compared to women and in Whites compared to other races, underscoring the need for targeted prevention and control strategies.

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Publication Details

Journal
Cureus
Published
2025-10-28
DOI
https://doi.org/10.7759/cureus.95552
Primary Topic
Hepatocellular Carcinoma Treatment and Prognosis
Type
article
Field-Weighted Citation Impact
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article

Trends and Disparities in Liver Cancer Incidence by Demographic Factors in the United States (1999-2020)

R. Seetharaman, Sanjay K. Mohanty, Md. Shohel Parvez, Shailza Dadwal et al.
Cureus
Hepatocellular Carcinoma Treatment and Prognosis
article

Trends and Disparities in Liver Cancer Incidence by Demographic Factors in the United States (1999-2020)

R. Seetharaman, Sanjay K. Mohanty, Md. Shohel Parvez, Shailza Dadwal, Karine Vartanian, Laxmi Mahita Reddy Paripati, Akshitha Talasila
article en

Abstract

This study shows state-wise variations in liver cancer incidence; however, crude rates per 100,000 remain relatively consistent across states. Over 22 years, liver cancer rates have increased, with the highest incidence found in men, White individuals, and those aged 65-74. Incidence increased for individuals over 45, but by the end of two decades, rates for ages 45-54 decreased while remaining high for ages ≥55. A more prominent upward trajectory was observed in men compared to women and in Whites compared to other races, underscoring the need for targeted prevention and control strategies.

CureusVol. 17(10)
Deccan College of Medical Sciences (IN), Sriram Chandra Bhanja Medical College Hospital (IN), Mamata Medical College (IN), Mahatma Gandhi Mission Institute of Health Sciences (IN), Mahatma Gandhi Mission Medical College and Hospital (IN), Dr. Reddy's Laboratories (India) (IN), Dr. Rajendra Prasad Government Medical College (IN), Southern California Orthopedic Institute (US)
Openalex Percentile: Top 59%
Hepatocellular Carcinoma Treatment and Prognosis
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