From early symptoms to EEG silence: tracking the neurodegenerative course of sporadic Creutzfeldt-Jakob disease

EEG, especially the early and highly prevalent presence of PSWCs, offers high diagnostic value in sCJD but does not serve as prognostic predictors. The close correlation between EEG decline and MRI progression supports multimodal monitoring. Serial EEG should be integrated into sCJD diagnosis and follow-up.

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Publication Details

Journal
Frontiers in Human Neuroscience
Published
2025-10-28
DOI
https://doi.org/10.3389/fnhum.2025.1652773
Primary Topic
Prion Diseases and Protein Misfolding
Type
article
Field-Weighted Citation Impact
0.00

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article

From early symptoms to EEG silence: tracking the neurodegenerative course of sporadic Creutzfeldt-Jakob disease

Liangliang Qiu, Yu He
Frontiers in Human Neuroscience
Prion Diseases and Protein Misfolding
article

From early symptoms to EEG silence: tracking the neurodegenerative course of sporadic Creutzfeldt-Jakob disease

Liangliang Qiu, Yu He
article en

Abstract

EEG, especially the early and highly prevalent presence of PSWCs, offers high diagnostic value in sCJD but does not serve as prognostic predictors. The close correlation between EEG decline and MRI progression supports multimodal monitoring. Serial EEG should be integrated into sCJD diagnosis and follow-up.

Frontiers in Human NeuroscienceVol. 19
Fujian Medical University (CN), First Affiliated Hospital of Fujian Medical University (CN)
National Natural Science Foundation of China
Openalex Percentile: Top 72%
Prion Diseases and Protein Misfolding
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