KBG syndrome complicated with chylothorax in a newborn: a case report and literature review
The newborn presented with KBGS complicated by chylothorax, attributable to a pathogenic variant in the <i>ANKRD11</i> gene. These results broaden the existing knowledge of KBGS clinical and genetic spectra. WES or whole-genome sequencing should be important in diagnosing patients with unexplained developmental abnormalities. It is imperative that the management for KBGS is multidisciplinary to deliver optimal prognosis and long-term outcomes.
Authors
- Yuqian Wang (ORCID: https://orcid.org/0000-0003-1769-6641)
- Xin Peng (ORCID: https://orcid.org/0000-0001-8535-1771)
- Xiaotong Yu (ORCID: https://orcid.org/0009-0007-7379-0241)
- Yang Liu (ORCID: https://orcid.org/0000-0002-8752-4346)
- Jing Zhu
- Ning Zou (ORCID: https://orcid.org/0000-0001-7438-7197)
Institutions
- Dalian Medical University (CN)
- Second Affiliated Hospital of Dalian Medical University (CN)
Publication Details
- Journal
- Frontiers in Pediatrics
- Published
- 2025-10-28
- DOI
- https://doi.org/10.3389/fped.2025.1690056
- Primary Topic
- Lymphatic Disorders and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Natural Science Foundation of China
- Dalian Medical University