Sexually Dimorphic Effects of a Single Neonatal Δ9-tetrahydrocannabinol Exposure on Neuronal Dendritic Morphology and Cognitive Functions in Rats
These findings demonstrate that a single neonatal THC exposure induces long-lasting, sex-dependent cognitive impairment and structural alterations in cortical and hippocampal neurons in rats. Our results underscore the vulnerability of the developing brain to cannabinoid exposure.
Authors
- Jeffrey W. Sall (ORCID: https://orcid.org/0000-0002-1725-5654)
- Jennifer Sasaki Russell
- Katrina Duong
- Gregory A. Chinn (ORCID: https://orcid.org/0000-0003-1743-3550)
- Judith Hellman (ORCID: https://orcid.org/0000-0003-2278-6625)
- Meetu Wadhwa
Institutions
- University of California, San Francisco (US)
Publication Details
- Journal
- Cannabis and Cannabinoid Research
- Published
- 2025-10-27
- DOI
- https://doi.org/10.1177/25785125251387835
- Primary Topic
- Cannabis and Cannabinoid Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00