Autopsy case: Vitiligo death from self-medication by <i>Ammi visnaga</i> poisoning

We report a fatal case of <i>Ammi visnaga</i> poisoning at Tangier's Forensic Medicine Department.An 18-year-old woman self-medicated with <i>Ammi visnaga</i> powder to treat her vitiligo. She experienced a wide range of symptoms and rapid clinical deterioration with a fatal outcome. The autopsy revealed lesions consistent with cutaneous vitiligo, necrosis of the liver, kidneys, lungs and pancreas. Toxicological and histological analysis confirmed chronic inflammation and acute systemic damage, highlighting <i>Ammi visnaga</i>'s potential toxicity. Its bioactive components vary, with the toxic dose estimated at 1 g per kg. This case demonstrates that prolonged consumption of herbal remedies like <i>Ammi visnaga</i> can be dangerous and indeed fatal. Raising public awareness on the dangers of self-medication and need for medical supervision and education on the dosage and side effects of <i>Ammi visnaga</i> is essential. The marketing of these products by non-professionals should be restricted.

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Publication Details

Journal
Medico-Legal Journal
Published
2025-10-27
DOI
https://doi.org/10.1177/00258172251337046
Primary Topic
melanin and skin pigmentation
Type
article
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article

Autopsy case: Vitiligo death from self-medication by Ammi visnaga poisoning

Samir Nya, Mohammed Ouali, Azeddine Essadi, Badreddine Zarhouni et al.
Medico-Legal Journal
melanin and skin pigmentation
article

Autopsy case: Vitiligo death from self-medication by Ammi visnaga poisoning

Samir Nya, Mohammed Ouali, Azeddine Essadi, Badreddine Zarhouni, Elias Mbuyi Numbi, Jihad Aarab, Rabi’a Benyousef
article en

Abstract

We report a fatal case of <i>Ammi visnaga</i> poisoning at Tangier's Forensic Medicine Department.An 18-year-old woman self-medicated with <i>Ammi visnaga</i> powder to treat her vitiligo. She experienced a wide range of symptoms and rapid clinical deterioration with a fatal outcome. The autopsy revealed lesions consistent with cutaneous vitiligo, necrosis of the liver, kidneys, lungs and pancreas. Toxicological and histological analysis confirmed chronic inflammation and acute systemic damage, highlighting <i>Ammi visnaga</i>'s potential toxicity. Its bioactive components vary, with the toxic dose estimated at 1 g per kg. This case demonstrates that prolonged consumption of herbal remedies like <i>Ammi visnaga</i> can be dangerous and indeed fatal. Raising public awareness on the dangers of self-medication and need for medical supervision and education on the dosage and side effects of <i>Ammi visnaga</i> is essential. The marketing of these products by non-professionals should be restricted.

Medico-Legal JournalVol. 94(1)
Abdelmalek Essaâdi University (MA), Université Mohammed VI des Sciences et de la Santé (MA)
Openalex Percentile: Top 67%
melanin and skin pigmentation
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Autopsy case: Vitiligo death from self-medication by <i>Ammi visnaga</i> poisoning — Samir Nya, Mohammed Ouali, et al. · Medico-Legal Journal (2025) | TGRS Research Map | TGRS