Detection of Lung Abnormalities in Patients With Rheumatoid Arthritis Who Smoke and Who Were Screened for Lung Cancer With Low‐Dose Chest Computed Tomography Imaging in Routine Clinical Care: Results From a Large Multihospital System
Patients with RA had higher prevalence of positive screening, fibrotic changes, and bronchiectasis detected by low-dose chest CT performed for lung cancer screening. Approximately one in four patients with RA who met US Preventive Services Task Force lung cancer screening criteria had a positive screen, whereas 1 in 20 had lung cancer. These results emphasize the importance of lung cancer screening among eligible patients with RA and may inform screening strategies for other lung abnormalities.
Authors
- Emily Kowalski
- Jeffrey A. Sparks (ORCID: https://orcid.org/0000-0002-5556-4618)
- Mark M. Hammer (ORCID: https://orcid.org/0000-0002-1700-7984)
- Gregory C McDermott (ORCID: https://orcid.org/0000-0002-9750-5448)
- Xiaosong Wang (ORCID: https://orcid.org/0000-0002-2663-8331)
- Misti L. Paudel (ORCID: https://orcid.org/0000-0002-8361-0650)
- Grace Qian (ORCID: https://orcid.org/0009-0000-7477-8657)
- Kathleen M.M. Vanni (ORCID: https://orcid.org/0000-0003-0839-9661)
- Suzanne Byrne (ORCID: https://orcid.org/0000-0001-7059-9774)
- Katarina J Bade
- Sung Hae Chang (ORCID: https://orcid.org/0000-0002-7980-7194)
- Pierre‐Antoine Juge (ORCID: https://orcid.org/0000-0002-3766-9600)
- Qianru Zhang (ORCID: https://orcid.org/0000-0001-9615-5768)
- Kevin T. Mueller
- Alene Saavedra
- Amie L. Samuylov
- Jessica A. Lorusso
Institutions
- Université Claude Bernard Lyon 1 (FR)
- Délégation Paris 5 (FR)
- Brigham and Women's Hospital (US)
- Harvard University (US)
- Inserm (FR)
- Université Paris Cité (FR)
- Soonchunhyang University (KR)
- Seoul Metropolitan Government (KR)
- Sorbonne Paris Cité (FR)
- SNUH SMG-SNU Boramae Medical Center (KR)
- Hôpital Bichat-Claude-Bernard (FR)
- Beijing Tsinghua Chang Gung Hospital (CN)
- Mass General Brigham (US)
- Tsinghua University (CN)
Publication Details
- Journal
- Arthritis Care & Research
- Published
- 2025-10-28
- DOI
- https://doi.org/10.1002/acr.25680
- Primary Topic
- Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
- Type
- article
- Field-Weighted Citation Impact
- 0.00