A fully automated explainable predictive model for diagnosing pre-capillary and post-capillary pulmonary hypertension on routine unenhanced CT: results from the ASPIRE registry
A fully automated model for multi-structure cardiothoracic segmentation on unenhanced CT is achievable. The model can predict PH and identify patients with pre-capillary PH and PH-LHD with promising performance.
Authors
- Ze Ming Goh (ORCID: https://orcid.org/0000-0001-8912-8470)
- Elliot W Checkley (ORCID: https://orcid.org/0000-0002-4136-3946)
- Khalid Alghamdi (ORCID: https://orcid.org/0000-0002-8535-0530)
- Krit Dwivedi (ORCID: https://orcid.org/0000-0003-4949-4550)
- David Gerard Kiely (ORCID: https://orcid.org/0000-0003-0184-6502)
- Jonathan Taylor (ORCID: https://orcid.org/0000-0003-3403-1668)
- Alireza Hokmabadi (ORCID: https://orcid.org/0000-0002-1407-4540)
- Pankaj Garg (ORCID: https://orcid.org/0000-0002-5483-169X)
- Georgia Hyde
- Lojain Abdulaal
- Peter Metherall
- Ahmed Maiter (ORCID: https://orcid.org/0000-0002-4999-2608)
- Mahan Salehi (ORCID: https://orcid.org/0000-0002-4064-4762)
- Michael J. Sharkey (ORCID: https://orcid.org/0000-0001-9851-0014)
- Samer Alabed (ORCID: https://orcid.org/0000-0002-9960-7587)
- Turki Nasser Alnasser (ORCID: https://orcid.org/0009-0004-8014-4924)
- Andrew J. Swift
Institutions
- University of East Anglia (GB)
- King Saud bin Abdulaziz University for Health Sciences (SA)
- King Abdullah International Medical Research Center (SA)
- Sheffield Teaching Hospitals NHS Foundation Trust (GB)
- Insigneo (GB)
- Sheffield Health and Social Care NHS Foundation Trust (GB)
- National Guard Health Affairs (SA)
- University of Sheffield (GB)
Publication Details
- Journal
- European Heart Journal - Digital Health
- Published
- 2025-10-25
- DOI
- https://doi.org/10.1093/ehjdh/ztaf124
- Primary Topic
- Pulmonary Hypertension Research and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Wellcome Trust
- National Institute for Health and Care Research
- Department of Health and Social Care