A GSH-consuming nanoamplifier for synergistic SO <sub>2</sub> gas therapy and ferroptosis promotion
A hyaluronic acid-modified nanotheranostic platform (Fe-DALN@HA) was constructed <i>via</i> Fe<sup>3+</sup>-coordinated self-assembly of a GSH-responsive SO<sub>2</sub> prodrug, enabling tumor-targeted delivery and synergistic induction of gas-enhanced ferroptosis through SO<sub>2</sub> gas release and the Fenton reaction for effective cancer therapy.
Authors
- Yan Miao (ORCID: https://orcid.org/0000-0001-7719-426X)
- Shouren Ge (ORCID: https://orcid.org/0000-0001-7460-7030)
- Yong Yao (ORCID: https://orcid.org/0000-0001-5566-4822)
- Yuxing Huang (ORCID: https://orcid.org/0000-0001-6012-8100)
- Yang Wang (ORCID: https://orcid.org/0000-0003-2500-5708)
- Tingting Chen (ORCID: https://orcid.org/0000-0002-4342-3236)
- Jin Wang (ORCID: https://orcid.org/0000-0002-0995-3890)
- Yan Cai (ORCID: https://orcid.org/0009-0009-4021-0882)
- Feng-Qin Wang (ORCID: https://orcid.org/0000-0002-5661-6651)
- Jian An (ORCID: https://orcid.org/0000-0001-5991-4497)
- Jiawen Yang (ORCID: https://orcid.org/0000-0002-1360-655X)
- Yan Xue
- G.-H. Huang
- Yawen Xu
- Yinfang Jiang
Institutions
- Nantong University (CN)
Publication Details
- Journal
- Chemical Communications
- Published
- 2025-01-01
- DOI
- https://doi.org/10.1039/d5cc05548b
- Citations
- 2
- Primary Topic
- Nanoplatforms for cancer theranostics
- Type
- article
- Field-Weighted Citation Impact
- 1.35