Intravenous Thrombolysis Prior to Endovascular Treatment in Basilar Artery Occlusions: A Patient Pooled Analysis of Four Randomized Controlled Trials
Findings from this patient-level pooled analysis of four randomized controlled trials suggest that bridging IVT over EVT alone was safe but not associated with significant improved outcomes. LEVEL OF EVIDENCE 2B: Level 2b, cohort study of a patient-level meta-analysis of 4 RCT's.
Authors
- Francisco Mont’Alverne (ORCID: https://orcid.org/0000-0002-1761-2674)
- Tudor G. Jovin (ORCID: https://orcid.org/0000-0002-2619-6975)
- Rui Liu (ORCID: https://orcid.org/0000-0002-3504-368X)
- Wim H. van Zwam (ORCID: https://orcid.org/0000-0003-1631-7056)
- Mohamed Fahmy Doheim (ORCID: https://orcid.org/0000-0001-8279-5078)
- Chuanhui Li (ORCID: https://orcid.org/0000-0003-1868-0211)
- Chunrong Tao (ORCID: https://orcid.org/0000-0002-5107-657X)
- Xunming Ji (ORCID: https://orcid.org/0000-0003-0293-2744)
- Wouter J. Schonewille (ORCID: https://orcid.org/0000-0002-4070-9730)
- Patrik Michel (ORCID: https://orcid.org/0000-0003-4954-7579)
- Pengfei Xu (ORCID: https://orcid.org/0000-0002-0389-1182)
- Robrecht R. M. M. Knapen (ORCID: https://orcid.org/0000-0003-4677-3685)
- Raul G. Nogueira (ORCID: https://orcid.org/0000-0003-4532-153X)
- Christiaan van der Leij (ORCID: https://orcid.org/0000-0003-0170-1012)
- Heinrich J. Audebert (ORCID: https://orcid.org/0000-0002-4785-0366)
- Robert J. van Oostenbrugge (ORCID: https://orcid.org/0000-0003-1032-9099)
- Volker Pütz
- Xinfeng Liu (ORCID: https://orcid.org/0000-0002-8182-9632)
- Wei Hu
- Qiliang Dai
Institutions
- University of Science and Technology of China (CN)
- University of Pittsburgh (US)
- Capital Medical University (CN)
- Maastricht University Medical Centre (NL)
- Maastricht University (NL)
- Cooper Medical School of Rowan University (US)
- St. Antonius Ziekenhuis (NL)
- University Hospital Carl Gustav Carus (DE)
- Hospital Geral de Fortaleza (BR)
- Jinling Institute of Technology (CN)
- Charité - Universitätsmedizin Berlin (DE)
- Nanjing University (CN)
- University of Lausanne (CH)
Publication Details
- Journal
- CardioVascular and Interventional Radiology
- Published
- 2025-10-27
- DOI
- https://doi.org/10.1007/s00270-025-04251-z
- Primary Topic
- Acute Ischemic Stroke Management
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Stryker
- Novo Nordisk