Myoepithelial Carcinoma Mimicking Basal Cell Carcinoma: A Case Report

We present the case of an 81-year-old male with a two-month history of a rapidly growing red nodule measuring 6 mm x 10 mm on his left malar cheek. Histological examination confirmed the diagnosis of myoepithelial carcinoma. The nodule was fully excised with a 3.8 mm radial margin and a close deep margin of 0.95 mm. This was followed by a wide local excision with a 5 mm margin, including subcutaneous fat up to the muscles of facial expression, and closed with a lateral cheek advancement flap per the specialist skin multidisciplinary team (SSMDT) recommendation. Postoperatively, the patient has been followed up as per the high-risk squamous cell carcinoma protocol, including four-monthly clinic reviews in the first year and six-monthly reviews in the second year. This case highlights the importance of raising awareness around cutaneous myoepithelial carcinoma's rare presentation and diagnostic challenges, and the importance of multidisciplinary management with long-term follow-up.

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Publication Details

Journal
Cureus
Published
2025-10-27
DOI
https://doi.org/10.7759/cureus.95526
Primary Topic
Salivary Gland Tumors Diagnosis and Treatment
Type
article
Field-Weighted Citation Impact
0.00
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article

Myoepithelial Carcinoma Mimicking Basal Cell Carcinoma: A Case Report

Soogan C. Lalla, Farlin Asharaff, Karwan Moutasim, Neena Nayak et al.
Cureus
Salivary Gland Tumors Diagnosis and Treatment
article

Myoepithelial Carcinoma Mimicking Basal Cell Carcinoma: A Case Report

Soogan C. Lalla, Farlin Asharaff, Karwan Moutasim, Neena Nayak, Roger Webb
article en

Abstract

We present the case of an 81-year-old male with a two-month history of a rapidly growing red nodule measuring 6 mm x 10 mm on his left malar cheek. Histological examination confirmed the diagnosis of myoepithelial carcinoma. The nodule was fully excised with a 3.8 mm radial margin and a close deep margin of 0.95 mm. This was followed by a wide local excision with a 5 mm margin, including subcutaneous fat up to the muscles of facial expression, and closed with a lateral cheek advancement flap per the specialist skin multidisciplinary team (SSMDT) recommendation. Postoperatively, the patient has been followed up as per the high-risk squamous cell carcinoma protocol, including four-monthly clinic reviews in the first year and six-monthly reviews in the second year. This case highlights the importance of raising awareness around cutaneous myoepithelial carcinoma's rare presentation and diagnostic challenges, and the importance of multidisciplinary management with long-term follow-up.

CureusVol. 17(10)
University Hospital Southampton NHS Foundation Trust (GB)
Openalex Percentile: Top 51%
Salivary Gland Tumors Diagnosis and Treatment
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