Time-dependent changes in pathological risk factors of recurrence after renal cell carcinoma surgery
Even with longer event-free time after surgery, improvements in subsequent C-RFS and CCSM were limited. Although the influence of most pathological risk factors diminished over time, LVI remained a consistent predictor of recurrence. These findings underscore the importance of postoperative strategies that account for the dynamic changes in pathological risk factors in RCC.
Authors
- Shuntaro Koda
- Keisuke Goto (ORCID: https://orcid.org/0000-0002-4165-1809)
- Nobuyuki Hinata (ORCID: https://orcid.org/0000-0001-7014-6812)
- Kohei Kobatake (ORCID: https://orcid.org/0000-0003-2098-3916)
- Yohei Sekino (ORCID: https://orcid.org/0000-0003-1525-5463)
- Yuki Kohada (ORCID: https://orcid.org/0000-0002-6510-7461)
- Akihiro Goriki
- Hiroyuki Shikuma (ORCID: https://orcid.org/0000-0003-4981-0074)
- Keisuke Hieda (ORCID: https://orcid.org/0000-0001-5182-8666)
- Yuichi Kadonishi
- Masanobu Shigeta (ORCID: https://orcid.org/0000-0002-4239-8040)
- Hiroyuki Kitano (ORCID: https://orcid.org/0000-0002-4756-2356)
- Akira Yano (ORCID: https://orcid.org/0000-0003-2935-0998)
- Mitsuru Kajiwara
Institutions
- Hiroshima University (JP)
- Mazda Motor Corporation (Japan) (JP)
- Hiroshima Prefectural Hospital (JP)
- Matsuyama Red Cross Hospital (JP)
- Kure Medical Center (JP)
- Onomichi General Hospital (JP)
Publication Details
- Journal
- Urologic Oncology Seminars and Original Investigations
- Published
- 2025-10-27
- DOI
- https://doi.org/10.1016/j.urolonc.2025.10.003
- Primary Topic
- Renal cell carcinoma treatment
- Type
- article
- Field-Weighted Citation Impact
- 0.00