Establishing an in vivo large animal model of one-lung ventilation and operative lung trauma
We describe a reproducible protocol for an in vivo large animal model of OLV lung surgery with a protective and two injurious mechanical ventilation arms with collection of physiologic data and biospecimens.
Authors
- Jay D. Kormish (ORCID: https://orcid.org/0000-0003-2974-8533)
- Shyamala Dakshinamurti (ORCID: https://orcid.org/0000-0001-7279-5226)
- Biniam Kidane (ORCID: https://orcid.org/0000-0002-2982-2505)
- Ruth M. Graham (ORCID: https://orcid.org/0000-0002-1130-8508)
- Catherine Giffin
- Martha Hinton
Institutions
- Children's Hospital Research Institute of Manitoba (CA)
- University of Manitoba (CA)
Publication Details
- Journal
- PLoS ONE
- Published
- 2025-10-27
- DOI
- https://doi.org/10.1371/journal.pone.0335012
- Primary Topic
- Respiratory Support and Mechanisms
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Health Sciences Centre Foundation
- University of Manitoba