Safety evaluation of cinacalcet: Signal mining and analysis of adverse events based on the FAERS database
Patient evaluation should be conducted prior to the clinical use of cinacalcet, particularly for individuals with heart failure, hepatic or renal insufficiency, and hypocalcemia. Close monitoring of electrolytes and vigilance for gastrointestinal, cardiovascular, and endocrine-related AEs are recommended. Prompt interventions should be implemented in cases of adverse reactions or disease progression to prevent serious complications or deterioration.
Authors
- Cheng Huang (ORCID: https://orcid.org/0000-0003-3769-7211)
- Na Yang (ORCID: https://orcid.org/0009-0008-3139-7422)
- Junxia Cao
Institutions
- Guiyang Medical University (CN)
- Guizhou Cancer Hospital (CN)
- Affiliated Hospital of Guizhou Medical University (CN)
Publication Details
- Journal
- PLoS ONE
- Published
- 2025-10-27
- DOI
- https://doi.org/10.1371/journal.pone.0331510
- Primary Topic
- Health Systems, Economic Evaluations, Quality of Life
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- U.S. Food and Drug Administration