Safety evaluation of cinacalcet: Signal mining and analysis of adverse events based on the FAERS database

Patient evaluation should be conducted prior to the clinical use of cinacalcet, particularly for individuals with heart failure, hepatic or renal insufficiency, and hypocalcemia. Close monitoring of electrolytes and vigilance for gastrointestinal, cardiovascular, and endocrine-related AEs are recommended. Prompt interventions should be implemented in cases of adverse reactions or disease progression to prevent serious complications or deterioration.

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Journal
PLoS ONE
Published
2025-10-27
DOI
https://doi.org/10.1371/journal.pone.0331510
Primary Topic
Health Systems, Economic Evaluations, Quality of Life
Type
article
Field-Weighted Citation Impact
0.00

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article

Safety evaluation of cinacalcet: Signal mining and analysis of adverse events based on the FAERS database

Cheng Huang, Na Yang, Junxia Cao
PLoS ONE
Health Systems, Economic Evaluations, Quality of Life
article

Safety evaluation of cinacalcet: Signal mining and analysis of adverse events based on the FAERS database

Cheng Huang, Na Yang, Junxia Cao
article en

Abstract

Patient evaluation should be conducted prior to the clinical use of cinacalcet, particularly for individuals with heart failure, hepatic or renal insufficiency, and hypocalcemia. Close monitoring of electrolytes and vigilance for gastrointestinal, cardiovascular, and endocrine-related AEs are recommended. Prompt interventions should be implemented in cases of adverse reactions or disease progression to prevent serious complications or deterioration.

PLoS ONEVol. 20(10)
Guiyang Medical University (CN), Guizhou Cancer Hospital (CN), Affiliated Hospital of Guizhou Medical University (CN)
U.S. Food and Drug Administration
Openalex Percentile: Top 60%
Health Systems, Economic Evaluations, Quality of Life
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Safety evaluation of cinacalcet: Signal mining and analysis of adverse events based on the FAERS database — Cheng Huang, Na Yang, et al. · PLoS ONE (2025) | TGRS Research Map | TGRS