Correcting for the Inflated Adult Population Denominator in an English Nationwide Health Care Cohort: Database Analysis Study
There are notable differences in the adult population size as per GDPPR when compared to census estimates. While the overall population size in the GDPPR data was seen to be inflated when compared to ONS census estimates, this was differential with respect to sociodemographic variables. A weighting-based approach can be applied to correct for the inflated denominator. Not correcting for it in large health care datasets, including the English NHS data, could introduce selection bias in epidemiological studies.
Authors
- Simon de Lusignan (ORCID: https://orcid.org/0000-0002-8553-2641)
- Richard Hobbs (ORCID: https://orcid.org/0000-0001-7976-7172)
- Chris Robertson (ORCID: https://orcid.org/0000-0001-6848-5241)
- Wilhelmine Meeraus
- Gavin Jamie (ORCID: https://orcid.org/0000-0001-9147-7784)
- Ruby S. M. Tsang (ORCID: https://orcid.org/0000-0002-2520-526X)
- Kathryn Taylor (ORCID: https://orcid.org/0000-0001-6589-5456)
- Xuejuan Fan (ORCID: https://orcid.org/0000-0002-0165-8344)
- Robert Williams (ORCID: https://orcid.org/0000-0002-1370-8898)
- Mark Joy (ORCID: https://orcid.org/0000-0002-4974-3724)
- Sneha Anand (ORCID: https://orcid.org/0000-0002-0538-3974)
- Debasish Kar (ORCID: https://orcid.org/0000-0002-1524-1312)
- Sudhir Venkatesan (ORCID: https://orcid.org/0000-0002-2093-5781)
- Sylvia Taylor (ORCID: https://orcid.org/0000-0001-7803-0611)
Institutions
- AstraZeneca (United Kingdom) (GB)
- University of Strathclyde (GB)
- University of Bristol (GB)
- University of Oxford (GB)
- AstraZeneca (South Korea) (KR)
- University of Plymouth (GB)
Publication Details
- Journal
- JMIR Public Health and Surveillance
- Published
- 2025-10-27
- DOI
- https://doi.org/10.2196/64788
- Primary Topic
- Global Health Care Issues
- Type
- article
- Field-Weighted Citation Impact
- 0.00