Acute Pancreatitis Following Diagnostic Oesophagogastroduodenoscopy: A Rare Post-procedure Complication

Acute pancreatitis is a recognised complication of endoscopic retrograde cholangiopancreatography (ERCP), but its occurrence after diagnostic oesophagogastroduodenoscopy (OGD) is exceedingly rare. We report a case of a woman who developed acute pancreatitis shortly after a diagnostic OGD during which a small peri-ampullary mucosal prominence was inadvertently biopsied. She presented with acute epigastric pain and was found to have imaging features consistent with pancreatitis in the absence of gallstones, alcohol use, or other causes. The patient was managed conservatively with intravenous fluids, analgesia, and gradual reintroduction of diet, leading to full clinical and radiological recovery. This case highlights an uncommon but important iatrogenic complication of diagnostic endoscopy and underscores the need for caution when performing biopsies near the ampulla of Vater, where minor trauma may precipitate transient pancreatic duct obstruction and pancreatitis.