Minimally invasive detection of early-stage opisthorchiasis-associated cholangiocarcinoma using label-free surface-enhanced Raman spectroscopy (SERS) of hamster serum
Our findings demonstrate that this cost-effective, label-free SERS approach can accurately detect precancerous and cancerous stages of cholangiocarcinoma in a hamster model, highlighting its strong potential for future development as a community-based screening tool.
Authors
- Thatsanapong Pongking (ORCID: https://orcid.org/0009-0006-4999-1038)
- Somchai Pinlaor (ORCID: https://orcid.org/0000-0002-8187-7247)
- Apisit Chaidee (ORCID: https://orcid.org/0000-0001-6495-0951)
- David Blair (ORCID: https://orcid.org/0000-0002-4658-3251)
- Tullayakorn Plengsuriyakarn (ORCID: https://orcid.org/0000-0002-4856-0555)
- Chawalit Pairojkul
- Keerapach Tunbenjasiri (ORCID: https://orcid.org/0009-0008-8464-7798)
- Suppakrit Kongsintaweesuk (ORCID: https://orcid.org/0009-0002-6276-5765)
- Naruechar Charoenram
- Aye Myat Mon (ORCID: https://orcid.org/0000-0002-2968-6654)
- Kesara Na-Bangchang
- Pakornkiat Tanasuka (ORCID: https://orcid.org/0009-0001-9735-028X)
Institutions
- Thammasat University (TH)
- Khon Kaen University (TH)
- James Cook University (AU)
Publication Details
- Journal
- PLoS ONE
- Published
- 2025-10-27
- DOI
- https://doi.org/10.1371/journal.pone.0334916
- Primary Topic
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Khon Kaen University
- National Science and Technology Development Agency
- National Research Council of Thailand
- Iran Telecommunication Research Center
- National Electronics and Computer Technology Center
- Thailand Science Research and Innovation
- National Institute of Information and Communications Technology