Ribociclib-Induced Hepatitis: A Case Report of Possible Autoimmune Hepatotoxicity
Ribociclib hepatotoxicity can be successfully treated with withdrawal of the medication and a short course of corticosteroids if liver enzymes do not improve following a 28-day withdrawal, highlighting a potential immune-mediated mechanism. Additionally, rechallenge with another cyclin-dependent kinase 4 and 6 inhibitor is a safe and effective strategy that should be considered.
Authors
- Javier Rivera (ORCID: https://orcid.org/0000-0001-8147-5881)
- M.H. Al-Sulaiman
- Christine Brezden‐Masley (ORCID: https://orcid.org/0000-0002-4818-318X)
- Jennifer Leigh
Institutions
- Mount Sinai Hospital (CA)
Publication Details
- Journal
- Case Reports in Oncology
- Published
- 2025-10-23
- DOI
- https://doi.org/10.1159/000549179
- Citations
- 2
- Primary Topic
- Neuroendocrine Tumor Research Advances
- Type
- article
- Field-Weighted Citation Impact
- 2.71