Diagnosis, diagnostic approach and challenges in pregnancy-associated AKI—the ADQI 32 consensus meeting
Despite advancements in obstetric care, pregnancy-associated acute kidney injury (PrAKI) continues to be a significant public health concern, contributing to substantial maternal and fetal morbidity and mortality. The most common causes of PrAKI include preeclampsia/eclampsia, haemorrhage, and infection. Diagnosis is influenced by gestational age and individual risk factors. Alongside traditional investigations such as imaging and kidney biopsy, novel diagnostics and biomarkers may provide valuable insights for differential diagnosis. This review aims to offer an update on the diagnostic approaches and investigational tools for PrAKI, while also addressing current challenges in the diagnostic paradigm and presenting recommendations for clinical practice and future research.
Authors
- Kate Bramham (ORCID: https://orcid.org/0000-0002-6272-7921)
- Rolando Claure‐Del Granado (ORCID: https://orcid.org/0000-0002-8163-3779)
- Nuttha Lumlertgul (ORCID: https://orcid.org/0000-0003-1506-4253)
- Swarnalata Gowrishankar (ORCID: https://orcid.org/0000-0002-4760-6259)
- Lizemarie Wium (ORCID: https://orcid.org/0000-0001-7949-7651)
- Rasha Samir Shemies (ORCID: https://orcid.org/0000-0002-0770-8023)
- Srinivas Samavedam (ORCID: https://orcid.org/0000-0001-6737-8663)
- Manjunath S Shetty (ORCID: https://orcid.org/0000-0001-9633-5670)
- Raghavan Murugan (ORCID: https://orcid.org/0000-0002-6823-6365)
- Shina Menon (ORCID: https://orcid.org/0000-0001-8473-0307)
- Manisha Sahay (ORCID: https://orcid.org/0000-0001-5534-2516)
- Manjusha Yadla
- Anjali Acharya (ORCID: https://orcid.org/0000-0002-5640-6881)
- Jorge Cerdá (ORCID: https://orcid.org/0000-0001-7058-1697)
- Harin Rhee (ORCID: https://orcid.org/0000-0001-6257-8551)
- Katherine Clark (ORCID: https://orcid.org/0000-0001-7149-2899)
- Raj Chakravarthi
- Carlos Eduardo Poli‐de‐Figueiredo (ORCID: https://orcid.org/0000-0002-7333-8884)
- Tarakeswari Surapaneni
- Marlies Ostermann (ORCID: https://orcid.org/0000-0001-9500-9080)
- Valérie A. Luyckx (ORCID: https://orcid.org/0000-0001-7066-8135)
- Claudio Ronco (ORCID: https://orcid.org/0000-0002-6697-4065)
- Ghada Ankawi (ORCID: https://orcid.org/0000-0002-8974-4350)
- KIANOUSH B KASHANI (ORCID: https://orcid.org/0000-0003-2184-3683)
- Ravindra L. Mehta (ORCID: https://orcid.org/0000-0002-0908-2968)
- Kate Wiles (ORCID: https://orcid.org/0000-0003-0617-8144)
- Nattachai Srisawat (ORCID: https://orcid.org/0000-0002-8544-8132)
- Raja Ramachandran
Institutions
- Chulalongkorn University (TH)
- University of San Diego (US)
- King's College London (GB)
- King Abdulaziz University (SA)
- Guy's and St Thomas' NHS Foundation Trust (GB)
- Jacobi Medical Center (US)
- King Chulalongkorn Memorial Hospital (TH)
- Universidad Mayor de San Simón (BO)
- University of California San Diego (US)
- Instituto Nacional de Salud (PE)
- Apollo Hospitals (IN)
- Apollo Hospitals (IN)
- International Renal Research Institute of Vicenza (IT)
Publication Details
- Journal
- Nephrology Dialysis Transplantation
- Published
- 2025-10-27
- DOI
- https://doi.org/10.1093/ndt/gfaf226
- Primary Topic
- Cardiovascular Issues in Pregnancy
- Type
- article
- Field-Weighted Citation Impact
- 0.00