TET exhibits enzymatic-independent and-dependent functions during Drosophila flight muscle development and aging
These results highlight the crucial role of TET beyond 5mC DNA oxidation, suggesting that both catalytic-dependent and catalytic-independent functions of TET are essential for muscle development and function in vivo.
Authors
- Yoan Renaud (ORCID: https://orcid.org/0000-0002-4036-8315)
- Émilie Plantié (ORCID: https://orcid.org/0000-0002-8703-7636)
- Lucas Waltzer
- Guillaume Junion (ORCID: https://orcid.org/0000-0003-0458-6021)
- Romane Bertrand
- Laurence Vandel (ORCID: https://orcid.org/0000-0002-3692-2942)
- Vincent Gerdy
Institutions
- Centre National de la Recherche Scientifique (FR)
- Inserm (FR)
- Université Clermont Auvergne (FR)
- University of Clermont Auvergne (FR)
- Sigma Clermont (FR)
- Clermont Université (FR)
- Institut Génétique, Reproduction et Développement (FR)
Publication Details
- Journal
- Skeletal Muscle
- Published
- 2025-10-27
- DOI
- https://doi.org/10.1186/s13395-025-00399-x
- Primary Topic
- Genetics, Aging, and Longevity in Model Organisms
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Agence Nationale de la Recherche
- Fondation pour la Recherche Médicale
- Ligue Contre le Cancer
- Institut National de Recherche pour l'Agriculture, l'Alimentation et l'Environnement