Extended-spectrum-β-lactamase-producing Gram-negative bacteria are associated with high mortality in children with bloodstream infections in Dar es Salaam, Tanzania
The rapidly increasing resistance to commonly used and affordable antibiotics increases the risk of death and prolongs hospital stays in neonates in the study setting. These findings highlight the need for strengthened infection prevention and control in community settings and appropriate antibiotic use to reduce the selection and spread of ESBL-GNB in hospitals.
Authors
- Joel Manyahi (ORCID: https://orcid.org/0000-0002-1388-3901)
- Adam Paul Roberts (ORCID: https://orcid.org/0000-0002-0760-3088)
- Bjørn Blomberg (ORCID: https://orcid.org/0000-0001-5647-4297)
- Said Aboud (ORCID: https://orcid.org/0000-0003-0981-3350)
- Sabrina John Moyo (ORCID: https://orcid.org/0000-0003-4735-1513)
- Nina Langeland (ORCID: https://orcid.org/0000-0003-0278-1616)
- Kristine Mørch (ORCID: https://orcid.org/0000-0002-6401-1353)
Institutions
- Norwegian Institute of Public Health (NO)
- Muhimbili University of Health and Allied Sciences (TZ)
- Liverpool School of Tropical Medicine (GB)
- Haukeland University Hospital (NO)
- National Institute for Medical Research (TZ)
- University of Bergen (NO)
Publication Details
- Journal
- BMC Infectious Diseases
- Published
- 2025-10-27
- DOI
- https://doi.org/10.1186/s12879-025-11629-4
- Citations
- 3
- Primary Topic
- Antibiotic Use and Resistance
- Type
- article
- Field-Weighted Citation Impact
- 3.79