Epigenetic modifications of the PHOX2A and CDH2 genes expression– new insights into the pathogenesis of multiple myeloma
Ultimately, identifying genes implicated in the progression of MM may pave the way for the refinement of current treatment protocols or the development of novel therapeutic strategies centred on epigenetic modifications or gene therapies. Additionally, the expression profile of circulating miRNAs may prove useful in selecting molecules that will constitute a good biomarker of disease progression from the preclinical to the fully symptomatic stage.
Authors
- M. Brzosko
- Alina Jurewicz (ORCID: https://orcid.org/0000-0002-2822-858X)
- Iga Stukan (ORCID: https://orcid.org/0000-0003-3560-6339)
- Andrzej Bohatyrewicz (ORCID: https://orcid.org/0000-0002-4773-0970)
- Karolina Łuczkowska (ORCID: https://orcid.org/0000-0003-4008-7473)
- Bogusław Machaliński (ORCID: https://orcid.org/0000-0002-6013-0419)
- Krzysztof Sommerfeld (ORCID: https://orcid.org/0000-0002-4339-8106)
- Piotr Kulig (ORCID: https://orcid.org/0000-0002-8695-8863)
- Bartłomiej Baumert (ORCID: https://orcid.org/0000-0001-9933-5844)
- Edyta Paczkowska (ORCID: https://orcid.org/0000-0001-7052-9741)
- Patrycja Stodolak (ORCID: https://orcid.org/0009-0009-6044-0474)
Institutions
- Pomeranian Medical University (PL)
Publication Details
- Journal
- BMC Cancer
- Published
- 2025-10-27
- DOI
- https://doi.org/10.1186/s12885-025-15030-x
- Primary Topic
- Multiple Myeloma Research and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 0.00