Sequential Combination of Unfavorable Histology, Followed by Clinical Stage M, Defines High-Risk Neuroblastoma: A Report from the Children’s Oncology Group
The benefits of using this new INPC-RG system are fourfold: (1) it allows for the rapid identification of group IV patients, (2) it lays the foundation for further refinement of group III, (3) it can stratify patients when the amount of tumor tissue is limited, and (4) it allows patients in resource-limited areas to be appropriately stratified, potentially improving the worldwide treatment of patients with neuroblastoma.
Authors
- Arlene Naranjo (ORCID: https://orcid.org/0000-0001-7737-4324)
- Wendy B. London (ORCID: https://orcid.org/0000-0003-3571-6538)
- John M. Maris (ORCID: https://orcid.org/0000-0002-8088-7929)
- Julie M. Gastier‐Foster (ORCID: https://orcid.org/0000-0001-7141-8031)
- Hiroyuki Shimada (ORCID: https://orcid.org/0000-0001-5025-7507)
- Julie R. Park (ORCID: https://orcid.org/0000-0002-6777-9165)
- Araz Marachelian (ORCID: https://orcid.org/0000-0003-3857-4782)
- Naohiko Ikegaki (ORCID: https://orcid.org/0000-0002-1838-284X)
- Susan L. Cohn (ORCID: https://orcid.org/0000-0001-5749-7650)
- Rochelle Bagatell (ORCID: https://orcid.org/0000-0002-5729-8819)
- Florette K. Hazard (ORCID: https://orcid.org/0000-0002-1538-0937)
- Meredith S. Irwin (ORCID: https://orcid.org/0000-0002-2452-5181)
- Serena Y. Tan (ORCID: https://orcid.org/0000-0001-5409-0695)
- Michael D. Hogarty (ORCID: https://orcid.org/0000-0002-9221-4852)
- Bill Chiu (ORCID: https://orcid.org/0000-0002-6540-4538)
- Angus M.S. Toland (ORCID: https://orcid.org/0000-0003-4453-7101)
- Nilsa C. Ramirez (ORCID: https://orcid.org/0000-0002-9945-9449)
- Jed G. Nuchtern (ORCID: https://orcid.org/0000-0002-5195-1661)
- Shalini C. Reshmi (ORCID: https://orcid.org/0000-0003-1491-077X)
- Shahab Asgharzadeh (ORCID: https://orcid.org/0000-0002-0510-3848)
- Eva Wagner (ORCID: https://orcid.org/0009-0001-8521-7967)
Institutions
- Children's Oncology Group (CH)
- University of Southern California (US)
- St. Jude Children's Research Hospital (US)
- Nationwide Children's Hospital (US)
- Children's Hospital of Philadelphia (US)
- Children's Hospital of Los Angeles (US)
- Palo Alto University (US)
- Baylor College of Medicine (US)
- University of Toronto (CA)
- Hospital for Sick Children (CA)
- University of Florida (US)
- University of Illinois Chicago (US)
- University of Chicago (US)
- Stanford Medicine (US)
- University of Southern California Sea Grant (US)
- Texas Children's Hospital (US)
- Dana-Farber/Boston Children's Cancer and Blood Disorders Center (US)
- University of Colorado Anschutz Medical Campus (US)
- University of California, Davis (US)
- Stanford University (US)
Publication Details
- Journal
- Clinical Cancer Research
- Published
- 2025-10-27
- DOI
- https://doi.org/10.1158/1078-0432.ccr-24-4369
- Citations
- 1
- Primary Topic
- Neuroblastoma Research and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 1.39