Comparison of the Long-Term Outcomes of Limb Salvage vs. Amputation in Lower Limb Vascular Trauma Patients: A 10-Year Follow-Up Study

Background Vascular revascularization of ischemic tissues is critical to prevent neuromuscular damage and preserve limb function. This study compared outcomes in lower limb trauma patients undergoing revascularization or amputation over a 10-year period. Methods We conducted a prospective observational study of 88 patients treated at a tertiary referring center. Demographic and injury data were collected, and functional outcomes have been allocated based on clinical criteria and surgeon judgment. Treatment outcomes included mortality, wound infection, rehabilitation requirements, and return to work. Results The amputation group was significantly older and experienced more surgical site infections than the revascularization group, whereas mortality and most functional outcomes did not differ significantly. Revascularization offered comparable long-term functional and psychosocial outcomes with fewer complications. Conclusions These findings suggest that when feasible, limb revascularization should be prioritized to optimize recovery and quality of life, as it yields similar survival and function with fewer complications than amputation.

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Publication Details

Journal
Cureus
Published
2025-10-27
DOI
https://doi.org/10.7759/cureus.95505
Primary Topic
Bone fractures and treatments
Type
article
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article

Comparison of the Long-Term Outcomes of Limb Salvage vs. Amputation in Lower Limb Vascular Trauma Patients: A 10-Year Follow-Up Study

Niki Tadayon, Sadegh Abaei, Samin Shokravi
Cureus
Bone fractures and treatments
article

Comparison of the Long-Term Outcomes of Limb Salvage vs. Amputation in Lower Limb Vascular Trauma Patients: A 10-Year Follow-Up Study

Niki Tadayon, Sadegh Abaei, Samin Shokravi
article en

Abstract

Background Vascular revascularization of ischemic tissues is critical to prevent neuromuscular damage and preserve limb function. This study compared outcomes in lower limb trauma patients undergoing revascularization or amputation over a 10-year period. Methods We conducted a prospective observational study of 88 patients treated at a tertiary referring center. Demographic and injury data were collected, and functional outcomes have been allocated based on clinical criteria and surgeon judgment. Treatment outcomes included mortality, wound infection, rehabilitation requirements, and return to work. Results The amputation group was significantly older and experienced more surgical site infections than the revascularization group, whereas mortality and most functional outcomes did not differ significantly. Revascularization offered comparable long-term functional and psychosocial outcomes with fewer complications. Conclusions These findings suggest that when feasible, limb revascularization should be prioritized to optimize recovery and quality of life, as it yields similar survival and function with fewer complications than amputation.

CureusVol. 17(10)
Shahid Beheshti University of Medical Sciences (IR)
Openalex Percentile: Top 59%
Bone fractures and treatments
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Comparison of the Long-Term Outcomes of Limb Salvage vs. Amputation in Lower Limb Vascular Trauma Patients: A 10-Year Follow-Up Study — Niki Tadayon, Sadegh Abaei, et al. · Cureus (2025) | TGRS Research Map | TGRS