Metformin use linked to decreased risk of pelvic organ prolapse: insights from NHANES data
This is the first clinical study that suggests metformin may reduce POP risk in specific high-inflammatory subgroups, potentially via anti-inflammatory pathways. The findings warrant further prospective studies and mechanistic validation.
Authors
- Linru Fu (ORCID: https://orcid.org/0000-0001-6368-5578)
- Zhao Tian (ORCID: https://orcid.org/0000-0001-9649-9405)
- Xiuqi Wang (ORCID: https://orcid.org/0000-0003-2033-9485)
- Zhijing Sun (ORCID: https://orcid.org/0000-0001-7187-0431)
- Xinyi Wang (ORCID: https://orcid.org/0009-0001-5802-7770)
- Zhe Du (ORCID: https://orcid.org/0000-0003-0311-2916)
- Tao Xu
Institutions
- Chinese Academy of Medical Sciences & Peking Union Medical College (CN)
- Peking Union Medical College Hospital (CN)
Publication Details
- Journal
- International Urology and Nephrology
- Published
- 2025-10-27
- DOI
- https://doi.org/10.1007/s11255-025-04849-9
- Primary Topic
- Pelvic floor disorders treatments
- Type
- article
- Field-Weighted Citation Impact
- 0.00