Dysregulated autophagy, neural signaling pathways and gut-brain axis in a novel vestibular migraine-like rat model: implications for pathogenesis
This validated VM-like rat model recapitulates core clinical and molecular features of VM. Gut dysbiosis and serum metabolic perturbations provide novel insights into the gut-brain axis in VM pathogenesis, suggesting potential therapeutic targets.
Authors
- Yan Ren (ORCID: https://orcid.org/0000-0001-6428-2252)
- Qijun Yu (ORCID: https://orcid.org/0000-0002-3724-0636)
- Yonghui Pan (ORCID: https://orcid.org/0000-0003-3094-3811)
- Changman Zhang
- Qingling Zhai (ORCID: https://orcid.org/0000-0003-1788-1687)
- Qihui Chen (ORCID: https://orcid.org/0000-0002-0944-0470)
- Shanshan Shi (ORCID: https://orcid.org/0000-0001-5702-6963)
- Tingting Sun (ORCID: https://orcid.org/0009-0003-7566-4629)
- Hongyan Li (ORCID: https://orcid.org/0000-0002-2191-1247)
- Changchang Ying (ORCID: https://orcid.org/0009-0004-0649-6630)
- Yanan Huang (ORCID: https://orcid.org/0000-0003-1873-5059)
- Jae-Jun Ban
Institutions
- Harbin Medical University (CN)
- First Affiliated Hospital of Harbin Medical University (CN)
Publication Details
- Journal
- The Journal of Headache and Pain
- Published
- 2025-10-27
- DOI
- https://doi.org/10.1186/s10194-025-02170-5
- Citations
- 3
- Primary Topic
- Migraine and Headache Studies
- Type
- article
- Field-Weighted Citation Impact
- 4.41
Funders
- Harbin Medical University
- National Natural Science Foundation of China