Association of leukocyte telomere length with anti-HBsAg antibody titer in Hepatitis-B recovered patients from the Pakistani population

A marked difference in the T/S ratio and number of base pairs was observed between the hepatitis-B recovered patients and normal control subjects. In chronic hepatitis-B recovered patients, the number of base pairs on each chromosome end were significantly higher as compared with normal control subjects. A weak positive correlation was noted between the T/S ratio and number of base pairs with anti-HBsAg antibody titer. This study shows that hepatitis-B recovered patients have maintained their higher telomere length as compared with the normal control subjects.

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Journal
BMC Infectious Diseases
Published
2025-10-27
DOI
https://doi.org/10.1186/s12879-025-11373-9
Primary Topic
Telomeres, Telomerase, and Senescence
Type
article
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article

Association of leukocyte telomere length with anti-HBsAg antibody titer in Hepatitis-B recovered patients from the Pakistani population

Asif Iqbal Khan, Ayub Qamar, Abdullah Khalid, Hui Liu et al.
BMC Infectious Diseases
Telomeres, Telomerase, and Senescence
article

Association of leukocyte telomere length with anti-HBsAg antibody titer in Hepatitis-B recovered patients from the Pakistani population

Asif Iqbal Khan, Ayub Qamar, Abdullah Khalid, Hui Liu, Dongmei Hu
article en

Abstract

A marked difference in the T/S ratio and number of base pairs was observed between the hepatitis-B recovered patients and normal control subjects. In chronic hepatitis-B recovered patients, the number of base pairs on each chromosome end were significantly higher as compared with normal control subjects. A weak positive correlation was noted between the T/S ratio and number of base pairs with anti-HBsAg antibody titer. This study shows that hepatitis-B recovered patients have maintained their higher telomere length as compared with the normal control subjects.

BMC Infectious DiseasesVol. 25(1)
Dalian Medical University (CN), Dow University of Health Sciences (PK)
Openalex Percentile: Top 61%
Telomeres, Telomerase, and Senescence
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Association of leukocyte telomere length with anti-HBsAg antibody titer in Hepatitis-B recovered patients from the Pakistani population — Asif Iqbal Khan, Ayub Qamar, et al. · BMC Infectious Diseases (2025) | TGRS Research Map | TGRS