Topical 5-fluorouracil 1% versus surgical removal as a primary treatment modality for ocular surface squamous neoplasia: a comparison of recurrences and side effects

Both 5-FU and surgical removal are effective and present a good security profile as primary therapies for OSSN. The two treatment modalities have no significant difference in the frequency of side effects or the time interval to recurrence.

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Publication Details

Journal
BMC Ophthalmology
Published
2025-10-27
DOI
https://doi.org/10.1186/s12886-025-04430-z
Citations
2
Primary Topic
Ocular Oncology and Treatments
Type
article
Field-Weighted Citation Impact
3.41
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article

Topical 5-fluorouracil 1% versus surgical removal as a primary treatment modality for ocular surface squamous neoplasia: a comparison of recurrences and side effects

Yuan Lin, Xianwen Xiao, Huping Wu, Xi Lan et al.
2 citations
BMC Ophthalmology
Ocular Oncology and Treatments
3.41
article

Topical 5-fluorouracil 1% versus surgical removal as a primary treatment modality for ocular surface squamous neoplasia: a comparison of recurrences and side effects

Yuan Lin, Xianwen Xiao, Huping Wu, Xi Lan, Dongyu Zhang, Shunrong Luo, Zhirong Lin, Hongwei Yan, Fang Xie, Xi Qin, Jintao Shi, Juan Yang, A. Liu, Zhiwen Xie
article en
2 citations

Abstract

Both 5-FU and surgical removal are effective and present a good security profile as primary therapies for OSSN. The two treatment modalities have no significant difference in the frequency of side effects or the time interval to recurrence.

BMC OphthalmologyVol. 25(1)
Xiamen University (CN), First Affiliated Hospital of Xiamen University (CN), Xiamen Blood Center (CN)
Openalex Percentile: Top 7%
Ocular Oncology and Treatments
3.41
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Topical 5-fluorouracil 1% versus surgical removal as a primary treatment modality for ocular surface squamous neoplasia: a comparison of recurrences and side effects — Yuan Lin, Xianwen Xiao, et al. · BMC Ophthalmology (2025) | TGRS Research Map | TGRS