Identification of coagulation-related biomarkers in osteoarthritis and immune infiltration analysis based on bioinformatics
This study, based on publicly available GEO datasets, identified six potential diagnostic biomarkers for OA: FAP, CTSH, MMP1, MMP9, C6, and MAFF. These findings highlight the potential involvement of coagulation-immune interactions in OA pathogenesis and offer novel insights into the molecular mechanisms and diagnostic strategies for the disease.
Authors
- Ping Zhou (ORCID: https://orcid.org/0000-0002-4183-0639)
- Zhixue Ou (ORCID: https://orcid.org/0000-0002-0595-6154)
- Siyuan Tong (ORCID: https://orcid.org/0000-0001-6517-6208)
- Liumei He (ORCID: https://orcid.org/0000-0001-5840-011X)
- Chu Liu (ORCID: https://orcid.org/0009-0003-9997-7101)
- Boyuan Qiu
- Zhihong Ou
Institutions
- Guangxi University of Chinese Medicine (CN)
- 181st Hospital of Chinese People's Liberation Army (CN)
- Affiliated Hospital of Guilin Medical College (CN)
Publication Details
- Journal
- Hereditas
- Published
- 2025-10-27
- DOI
- https://doi.org/10.1186/s41065-025-00585-3
- Primary Topic
- Myeloproliferative Neoplasms: Diagnosis and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Natural Science Foundation of Guangxi Province