The correlation of DPM1 overexpression with immune infiltration and poor prognosis in hepatocellular carcinoma
DPM1 serves as a promising prognostic biomarker in HCC, with its expression correlating with unfavorable clinical outcomes and immune landscape alterations. Future studies should further validate DPM1's impact on ferroptosis and immune evasion in HCC, and explore its potential as a therapeutic target.
Authors
- Laiwei You (ORCID: https://orcid.org/0000-0001-8713-2660)
- Yong Cheng (ORCID: https://orcid.org/0000-0002-9314-0971)
- Huan Wang (ORCID: https://orcid.org/0000-0003-1115-143X)
- Hao Li (ORCID: https://orcid.org/0000-0002-9886-1874)
- Yang Zhou (ORCID: https://orcid.org/0009-0001-7895-7780)
- Jianrong Guo (ORCID: https://orcid.org/0009-0005-1064-025X)
Institutions
- Second Military Medical University (CN)
- Ningxia Medical University (CN)
- Shanghai Pudong New Area Gongli Hospital (CN)
Publication Details
- Journal
- Discover Oncology
- Published
- 2025-10-27
- DOI
- https://doi.org/10.1007/s12672-025-03592-y
- Primary Topic
- Ferroptosis and cancer prognosis
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Natural Science Foundation of China