Effect of isotretinoin on sperm quality in humans: an <i>in vitro</i> model

Knowing that the concentrations achieved clinically in semen and blood are considerably lower than the cytotoxic concentration, these findings suggest that treatment with therapeutic doses of isotretinoin does not compromise human sperm function in vitro.

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Publication Details

Journal
Archivio Italiano di Urologia e Andrologia
Published
2025-10-27
DOI
https://doi.org/10.4081/aiua.2025.14440
Primary Topic
Acne and Rosacea Treatments and Effects
Type
article
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0.00
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article

Effect of isotretinoin on sperm quality in humans: an in vitro model

Walter D. Cardona Maya, Sofia Álzate Aristizábal
Archivio Italiano di Urologia e Andrologia
Acne and Rosacea Treatments and Effects
article

Effect of isotretinoin on sperm quality in humans: an in vitro model

Walter D. Cardona Maya, Sofia Álzate Aristizábal
article en

Abstract

Knowing that the concentrations achieved clinically in semen and blood are considerably lower than the cytotoxic concentration, these findings suggest that treatment with therapeutic doses of isotretinoin does not compromise human sperm function in vitro.

Archivio Italiano di Urologia e AndrologiaVol. 97(4)
Universidad de Antioquia (CO)
Openalex Percentile: Top 48%
Acne and Rosacea Treatments and Effects
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Effect of isotretinoin on sperm quality in humans: an <i>in vitro</i> model — Walter D. Cardona Maya, Sofia Álzate Aristizábal · Archivio Italiano di Urologia e Andrologia (2025) | TGRS Research Map | TGRS