Long-term persistence with guselkumab: a 5-year multicenter retrospective study across 14 dermatology centers in Italy
Guselkumab demonstrated high long-term persistence in real-world clinical practice. Drug survival remained consistently high across various subgroups, with prior IL-17 inhibitor exposure being the main predictor of decreased persistence.
Authors
- Giovanni Pellacani (ORCID: https://orcid.org/0000-0002-7222-2951)
- Vincenzo Panasiti (ORCID: https://orcid.org/0000-0003-1589-867X)
- Emanuele Miraglia (ORCID: https://orcid.org/0000-0002-4301-5857)
- Maria Esposito (ORCID: https://orcid.org/0000-0002-4773-6993)
- Annunziata Dattola (ORCID: https://orcid.org/0000-0001-9504-5882)
- Federica Trovato (ORCID: https://orcid.org/0009-0002-9092-6183)
- Oriana Simonetti (ORCID: https://orcid.org/0000-0001-7941-5089)
- Nicoletta Bernardini (ORCID: https://orcid.org/0000-0002-6295-3574)
- Pier Luigi Bruni
- Paolo Amerio (ORCID: https://orcid.org/0000-0003-1589-9672)
- Antonio Giovanni Richetta
- Maria Concetta Fargnoli (ORCID: https://orcid.org/0000-0002-7249-2556)
- Concetta Potenza (ORCID: https://orcid.org/0000-0002-6300-8697)
- Gaia Moretta (ORCID: https://orcid.org/0000-0002-8839-5961)
- Giacomo Caldarola (ORCID: https://orcid.org/0000-0002-8837-9232)
- Cristina Mugheddu (ORCID: https://orcid.org/0000-0001-7500-4178)
- Elisa Molinelli (ORCID: https://orcid.org/0000-0002-7939-0026)
- Gianluca Pagnanelli (ORCID: https://orcid.org/0000-0003-0961-6779)
- Ketty Peris (ORCID: https://orcid.org/0000-0002-5237-0463)
- Jasmine Anedda (ORCID: https://orcid.org/0000-0002-7176-381X)
- Sabatino Pallotta (ORCID: https://orcid.org/0000-0003-4827-2892)
- Severino Persechino (ORCID: https://orcid.org/0000-0002-3728-5877)
- Domenico Giordano
- Dario Graceffa (ORCID: https://orcid.org/0000-0003-2811-781X)
- Annamaria Mazzotta
- C. Bonifati
- Edvige Morea
Institutions
- Università Campus Bio-Medico (IT)
- University of Cagliari (IT)
- Policlinico Umberto I (IT)
- Agostino Gemelli University Polyclinic (IT)
- San Salvatore Hospital (IT)
- Fondazione G.B. Bietti (IT)
- Azienda Ospedaliero Universitaria Ospedali Riuniti (IT)
- CTO Andrea Alesini (IT)
- San Gallicano Hospital (IT)
- Campus Bio Medico University Hospital (IT)
- Carlo Forlanini Hospital (IT)
- ASM Terni (Italy) (IT)
- Agenzia Sanitaria Regionale Abruzzo (IT)
- Sapienza University of Rome (IT)
Publication Details
- Journal
- Dermatology Practical & Conceptual
- Published
- 2025-10-27
- DOI
- https://doi.org/10.5826/dpc.1504a6646
- Primary Topic
- Psoriasis: Treatment and Pathogenesis
- Type
- article
- Field-Weighted Citation Impact
- 0.00