Safe delivery of a highly toxic anthracycline derivative through liposomal nanoformulation achieves complete cancer regression
Liposomal formulations of extremely cytotoxic anthracycline analogs, such as LiPyDau, represent a promising and highly effective therapeutic approach for combating drug resistant cancer.
Authors
- Balázs Gombos
- Zoltán Varga (ORCID: https://orcid.org/0000-0002-5741-2669)
- Péter Pokreisz (ORCID: https://orcid.org/0000-0003-2810-9000)
- Gergő Barta (ORCID: https://orcid.org/0000-0002-9854-0341)
- Szilárd Tóth (ORCID: https://orcid.org/0000-0002-0168-3531)
- Kristóf Hegedüs (ORCID: https://orcid.org/0000-0002-8385-097X)
- Eszter Bajtai
- Mihály Cserepes (ORCID: https://orcid.org/0000-0003-4816-2618)
- Csaba Magyar (ORCID: https://orcid.org/0000-0002-5023-6180)
- Gergely Szakács (ORCID: https://orcid.org/0000-0002-9311-7827)
- Anikó Gaál (ORCID: https://orcid.org/0000-0003-4064-1825)
- Zsuzsanna Helyes (ORCID: https://orcid.org/0000-0003-2435-4367)
- Agnes Csiszar (ORCID: https://orcid.org/0000-0001-7911-3427)
- Lívia Naszályi Nagy (ORCID: https://orcid.org/0000-0003-2799-1150)
- Sandra Högler (ORCID: https://orcid.org/0000-0002-6899-5273)
- Pál Tamás Szabó (ORCID: https://orcid.org/0000-0003-2260-4641)
- Lukas Kenner (ORCID: https://orcid.org/0000-0003-2184-1338)
- James Cowles
- Dávid Szüts (ORCID: https://orcid.org/0000-0001-7985-0136)
- Krisztina Kiss (ORCID: https://orcid.org/0000-0002-6989-5098)
- András Füredi (ORCID: https://orcid.org/0000-0002-7883-9901)
- Zoltán Szeltner
- József Tóvári (ORCID: https://orcid.org/0000-0002-5543-3204)
- Gábor Mező (ORCID: https://orcid.org/0000-0002-7618-7954)
- Dániel Kiss (ORCID: https://orcid.org/0000-0002-8482-8862)
- Kata Bölcskei (ORCID: https://orcid.org/0000-0002-3008-4538)
- Attila Kiss
Institutions
- Semmelweis University (HU)
- Obuda University (HU)
- Eötvös Loránd University (HU)
- Hungarian Central Statistical Office (HU)
- University of Veterinary Medicine Vienna (AT)
- Budapest University of Technology and Economics (HU)
- Comprehensive Cancer Center Vienna (AT)
- Institute of Materials and Environmental Chemistry (HU)
- National Institute of Oncology (HU)
- National Research, Development and Innovation Office (HU)
- National Center for Epidemiology (HU)
- HUN-REN Centre for Energy Research (HU)
- Hungarian Academy of Sciences (HU)
- Medical University of Vienna (AT)
- University of Pecs (HU)
- HUN-REN Research Centre for Natural Sciences (HU)
Publication Details
- Journal
- Molecular Cancer
- Published
- 2025-10-27
- DOI
- https://doi.org/10.1186/s12943-025-02444-1
- Citations
- 3
- Primary Topic
- Nanoparticle-Based Drug Delivery
- Type
- article
- Field-Weighted Citation Impact
- 1.79
Funders
- European Commission
- Austrian Science Fund
- Universität Wien
- Medizinische Universität Wien
- National Research, Development and Innovation Office
- H2020 Marie Skłodowska-Curie Actions