Therapeutic efficacy of the drug ASD®-10 in the treatment of pig wounds

The company AVZ Ltd (Russia) has developed a new pharmaceutical form of the well-known ASD drug. The medicinal product ASD®-10 is available in the form of an aerosol for external use. As active ingredients it contains: ASD-2F-substance, ASD-3F-substance and auxiliary substances. The drug belongs to the group of antiseptic and dermatotropic agents, improves metabolic processes in the focus of inflammation, has a local wound healing, anti-inflammatory, antiseptic effect, stimulates the activity of the reticuloendothelial system, inhibits the growth of pathogenic microflora, normalizes trophism and accelerates the repair of damaged tissues. Purpose of the study: to investigate the therapeutic efficacy of the veterinary drug ASD®-10 in the treatment of surgical and traumatic wounds in pigs. Materials and methods: The studies were conducted on 100 pigs, which were divided into 2 experimental groups: with fresh wounds after castration (n=50) and with wounds in the tail area as a result of cannibalism (n=50). In the piglets of the first experimental group, the drug was applied once externally to the wound surface immediately after castration. In the pigs of the second experimental group, the drug was applied externally to the damaged area of the skin once a day daily for 7 days. Results and conclusions. In piglets of the first group, complete healing of the postoperative wound occurred on the 7th day after castration and a single treatment with ASD®-10. As a result of systematic treatment of the surface of tissue defects with the test drug on the 7th day, all experimental animals of the second group had a scab on the wound surface and a decrease in the intensity of tissue edema occurred, there were no exudative manifestations. After the course of treatment, 66.7% of the previous species composition of microorganisms was completely eliminated. The drug is well tolerated by animals, promotes complete clinical recovery, improves bacteriological parameters, and does not cause adverse events and negative reactions.