Pseudoporphyria triggered by ultraviolet A radiation exposure: the under-reported role of sunbeds and nail lamps

Pseudoporphyria is an uncommon photodistributed bullous disease with clinical and histopathological features of porphyria cutanea tarda but without biochemical porphyrin abnormalities. Its pathogenesis is not fully understood; associations with chronic renal failure, dialysis, medications (such as antibiotics, chemotherapy agents and diuretics) and excessive sun exposure have been documented. However, pseudoporphyria secondary to artificial sources of ultraviolet radiation is rarely reported. We highlight the case of a patient with pseudoporphyria associated with frequent use of an ultraviolet A tanning bed and nail-curing lamp whose symptoms resolved following cessation of exposure.

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Publication Details

Journal
Clinical and Experimental Dermatology
Published
2025-10-24
DOI
https://doi.org/10.1093/ced/llaf475
Primary Topic
Porphyrin Metabolism and Disorders
Type
article
Field-Weighted Citation Impact
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article

Pseudoporphyria triggered by ultraviolet A radiation exposure: the under-reported role of sunbeds and nail lamps

Kate Short, William Fostier, Bayanne Olabi, Michael Alexander et al.
Clinical and Experimental Dermatology
Porphyrin Metabolism and Disorders
article

Pseudoporphyria triggered by ultraviolet A radiation exposure: the under-reported role of sunbeds and nail lamps

Kate Short, William Fostier, Bayanne Olabi, Michael Alexander, Sophie Weatherhead, Jonathan Lye
article en

Abstract

Pseudoporphyria is an uncommon photodistributed bullous disease with clinical and histopathological features of porphyria cutanea tarda but without biochemical porphyrin abnormalities. Its pathogenesis is not fully understood; associations with chronic renal failure, dialysis, medications (such as antibiotics, chemotherapy agents and diuretics) and excessive sun exposure have been documented. However, pseudoporphyria secondary to artificial sources of ultraviolet radiation is rarely reported. We highlight the case of a patient with pseudoporphyria associated with frequent use of an ultraviolet A tanning bed and nail-curing lamp whose symptoms resolved following cessation of exposure.

Clinical and Experimental DermatologyVol. 51(3)
Royal Victoria Infirmary (GB), Clinical Research Institute (US), University of Newcastle Australia (AU), Newcastle University (GB)
Openalex Percentile: Top 73%
Porphyrin Metabolism and Disorders
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