CMR-based assessment of long-term effects of tafamidis in patients with cardiac transthyretin amyloidosis

Substantial worsening of clinical symptoms, serum biomarkers, and imaging parameters occurred in both tafamidis-treated and tafamidis-naïve ATTR-CM patients within a follow-up period of approximately 2 years. However, the "extent of worsening" is significantly lower in the tafamidis-treated compared to the tafamidis-naïve patients.

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Publication Details

Journal
Clinical Research in Cardiology
Published
2025-10-27
DOI
https://doi.org/10.1007/s00392-025-02691-8
Primary Topic
Amyloidosis: Diagnosis, Treatment, Outcomes
Type
article
Field-Weighted Citation Impact
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article

CMR-based assessment of long-term effects of tafamidis in patients with cardiac transthyretin amyloidosis

Claudia Meier, Khuraman Isgandarova, Volker Vehof, Philipp Stalling et al.
Clinical Research in Cardiology
Amyloidosis: Diagnosis, Treatment, Outcomes
article

CMR-based assessment of long-term effects of tafamidis in patients with cardiac transthyretin amyloidosis

Claudia Meier, Khuraman Isgandarova, Volker Vehof, Philipp Stalling, Michael Bietenbeck, Alexandru Zlibut, Maria Theofanidou, Ali Yılmaz, Nuriye Akyol, Redouane Bouras
article en

Abstract

Substantial worsening of clinical symptoms, serum biomarkers, and imaging parameters occurred in both tafamidis-treated and tafamidis-naïve ATTR-CM patients within a follow-up period of approximately 2 years. However, the "extent of worsening" is significantly lower in the tafamidis-treated compared to the tafamidis-naïve patients.

Clinical Research in Cardiology
University Hospital Münster (DE)
Openalex Percentile: Top 73%
Amyloidosis: Diagnosis, Treatment, Outcomes
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