Behaviours that challenge in children with intellectual disability: systematic review and meta-analysis of pharmacological and non-pharmacological interventions

It is important to note that most studies included were conducted in Western countries and had small sample sizes, and findings may be due to the outcome measures used. Findings support current recommendations that non-pharmacological interventions should be first-line treatment for behaviours that challenge in this population. Evidence highlighted the need for better quality, adequately powered randomised controlled trials.

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Publication Details

Journal
BJPsych Open
Published
2025-10-27
DOI
https://doi.org/10.1192/bjo.2025.10871
Primary Topic
Family and Disability Support Research
Type
article
Field-Weighted Citation Impact
0.00
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article

Behaviours that challenge in children with intellectual disability: systematic review and meta-analysis of pharmacological and non-pharmacological interventions

Valerie Lye, Sohil Alqazlan, Angela Hassiotis, Elitsa Dimitrova et al.
BJPsych Open
Family and Disability Support Research
article

Behaviours that challenge in children with intellectual disability: systematic review and meta-analysis of pharmacological and non-pharmacological interventions

Valerie Lye, Sohil Alqazlan, Angela Hassiotis, Elitsa Dimitrova, Vasiliki Totsika, Borbala Vegh, Amanda Timmerman
article en

Abstract

It is important to note that most studies included were conducted in Western countries and had small sample sizes, and findings may be due to the outcome measures used. Findings support current recommendations that non-pharmacological interventions should be first-line treatment for behaviours that challenge in this population. Evidence highlighted the need for better quality, adequately powered randomised controlled trials.

BJPsych OpenVol. 11(6)
Imam Mohammad ibn Saud Islamic University (SA), Islamic University (BD), University College London (GB)
Openalex Percentile: Top 57%
Family and Disability Support Research
DOIOpen Access PDFOpenAlex
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Behaviours that challenge in children with intellectual disability: systematic review and meta-analysis of pharmacological and non-pharmacological interventions — Valerie Lye, Sohil Alqazlan, et al. · BJPsych Open (2025) | TGRS Research Map | TGRS