Association of GABRG2 gene polymorphisms with idiopathic generalized epilepsy in Egyptian children: a case–control study
The T allele and TT genotype of the GABRG2 C588T gene were more common among patients with IGE, whereas the G allele and the GG genotype of the GABRG2 3145G>A gene may be significant predictors of ASMs resistance among IGE patients. Results validation in larger, multi-center studies across diverse populations is recommended.
Authors
- Sohier Yahia (ORCID: https://orcid.org/0000-0002-6974-5997)
- Yahya Wahba (ORCID: https://orcid.org/0000-0001-7479-7866)
- Nora El-Tantawy (ORCID: https://orcid.org/0000-0002-2054-6081)
- Mohamed Khodair (ORCID: https://orcid.org/0000-0002-3303-0543)
- Hiba B. Khalil
- Abdel‐Hady El‐Gilany (ORCID: https://orcid.org/0000-0001-9376-6985)
- Hanan S. Sherbiny
- Doaa Shahin (ORCID: https://orcid.org/0000-0001-5013-6924)
- Khadeja Mohamed Soheeb
Institutions
- Alfaisal University (SA)
- Mansoura University (EG)
- Al Zawiya University (LY)
- Imam Abdulrahman Al Faisal Hospital (SA)
- University of Bisha (SA)
- October 6 University (EG)
- Al Baha University (SA)
Publication Details
- Journal
- European journal of medical research
- Published
- 2025-10-27
- DOI
- https://doi.org/10.1186/s40001-025-03230-x
- Citations
- 1
- Primary Topic
- Epilepsy research and treatment
- Type
- article
- Field-Weighted Citation Impact
- 1.47
Funders
- Science and Technology Development Fund