Ginsenoside Ro alleviated cuproptosis induced by high oxalate via inhibiting zinc transporter ZnT1 in renal tubular epithelial cells
This study provided evidence that Ro mitigated cuproptosis HK-2 cells induced by high oxalate through inhibiting ZnT1, thus effectively suppressing oxidative stress and crystal deposition triggered by high oxalate.
Authors
- Shujue Li
- Wenqi Wu (ORCID: https://orcid.org/0000-0002-3923-3093)
- Xiaoling Ying
- Junliang Fu (ORCID: https://orcid.org/0009-0001-8318-6888)
- Hong Yang (ORCID: https://orcid.org/0000-0003-1250-5156)
- Zhuojia Li
- Beixin Yu (ORCID: https://orcid.org/0000-0002-1920-1529)
- Chuan Li (ORCID: https://orcid.org/0000-0001-5539-6557)
- Yuhao Zhou (ORCID: https://orcid.org/0000-0002-9805-0895)
- Shike Zhang (ORCID: https://orcid.org/0000-0003-4131-7568)
- Jia Zeng (ORCID: https://orcid.org/0000-0002-9447-2791)
- Yuxi Nie
- Liang Han (ORCID: https://orcid.org/0000-0002-5226-5508)
Institutions
- Macau University of Science and Technology (MO)
- Beijing University of Chinese Medicine (CN)
- University of Macau (MO)
- Second Affiliated Hospital of Guangzhou Medical University (CN)
- First Affiliated Hospital of Guangzhou Medical University (CN)
- Guangzhou Medical University (CN)
Publication Details
- Journal
- Journal of Ginseng Research
- Published
- 2025-10-27
- DOI
- https://doi.org/10.1016/j.jgr.2025.10.005
- Primary Topic
- Trace Elements in Health
- Type
- article
- Field-Weighted Citation Impact
- 0.00