Use and efficacy of antifibrinolytic agents in patients undergoing growth-friendly surgery for neuromuscular scoliosis

AF agents are being used for patients undergoing growth-friendly procedures with TXA being the most commonly used AF. However, there is no significant difference in EBL, cell saver volume, and intraoperative or postoperative transfusion rates between patients that do or do not receive AF agents for these procedures. Additional studies are needed to validate these results, as well as determine their efficacy, safety, and value in this medically fragile group.

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Publication Details

Journal
Spine Deformity
Published
2025-10-27
DOI
https://doi.org/10.1007/s43390-025-01214-9
Primary Topic
Cardiac, Anesthesia and Surgical Outcomes
Type
article
Field-Weighted Citation Impact
0.00
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article

Use and efficacy of antifibrinolytic agents in patients undergoing growth-friendly surgery for neuromuscular scoliosis

Ishaan Swarup, John D. Smith, Jasmine Dosanjh, Paul D. Sponseller et al.
Spine Deformity
Cardiac, Anesthesia and Surgical Outcomes
article

Use and efficacy of antifibrinolytic agents in patients undergoing growth-friendly surgery for neuromuscular scoliosis

Ishaan Swarup, John D. Smith, Jasmine Dosanjh, Paul D. Sponseller, Peter Strum, Wei Wu
article en

Abstract

AF agents are being used for patients undergoing growth-friendly procedures with TXA being the most commonly used AF. However, there is no significant difference in EBL, cell saver volume, and intraoperative or postoperative transfusion rates between patients that do or do not receive AF agents for these procedures. Additional studies are needed to validate these results, as well as determine their efficacy, safety, and value in this medically fragile group.

Spine DeformityVol. 14(2)
Cincinnati Children's Hospital Medical Center (US), Johns Hopkins University (US), University of California, San Francisco (US), Johns Hopkins Medicine (US), UCSF Benioff Children's Hospital (US)
Openalex Percentile: Top 53%
Cardiac, Anesthesia and Surgical Outcomes
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