Ru( <scp>ii</scp> )-catalyzed stereoselective C(7)–H α-fluoroalkenylation of indolines
An efficient method for a ruthenium(II)-catalyzed stereoselective C(7)-H α-fluoroalkenylation of indolines is described. The protocol exhibits good functional group compatibility. The corresponding C7 fluoroalkenylated indolines can be obtained in moderate to excellent yields under mild and convenient conditions. Furthermore, two products synthesized using this method show antibacterial activity against <i>Staphylococcus aureus</i>.
Authors
- Gaorong Wu (ORCID: https://orcid.org/0000-0002-6558-0662)
- Shunli Xiao
- Hao Huang (ORCID: https://orcid.org/0000-0001-5174-0920)
- Xingwang Liu (ORCID: https://orcid.org/0000-0002-4783-5123)
- W. P. Lai
- Lele Bai
Institutions
- Huaihua University (CN)
- Gannan Medical University (CN)
Publication Details
- Journal
- Chemical Communications
- Published
- 2025-01-01
- DOI
- https://doi.org/10.1039/d5cc05503b
- Primary Topic
- Fluorine in Organic Chemistry
- Type
- article
- Field-Weighted Citation Impact
- 0.00