Electroacupuncture for chemotherapy-induced gastrointestinal symptoms in colorectal cancer: protocol for a multicenter, three-arm, randomized controlled trial
This multicenter RCT is designed to generate high-quality evidence on the comprehensive efficacy of EA in addressing chemotherapy-induced GI toxicity in CRC patients. If proven effective, EA could provide a safe, non-pharmacological adjunct to standard care, helping to reduce symptom burden and improve patient adherence to chemotherapy. Trial registration ChiCTR2200062317. Registered on 1 August 2022.
Authors
- Xueli Zhou (ORCID: https://orcid.org/0000-0002-5267-9444)
- Zi-Wen Chen
- Yun-Jie Shu
- Mingsheng Sun (ORCID: https://orcid.org/0000-0002-6748-5087)
- Qifu Li (ORCID: https://orcid.org/0000-0003-3904-410X)
- Zi-Han Yin
- Ling Zhao
- Tao Xu (ORCID: https://orcid.org/0000-0003-1984-1689)
- Fanrong Liang (ORCID: https://orcid.org/0000-0001-8518-9268)
Institutions
- Sichuan University (CN)
- West China Hospital of Sichuan University (CN)
- Sichuan Provincial Hospital of Traditional Chinese Medicine (CN)
- Chengdu University of Traditional Chinese Medicine (CN)
Publication Details
- Journal
- International Journal of Colorectal Disease
- Published
- 2025-10-27
- DOI
- https://doi.org/10.1007/s00384-025-05008-3
- Primary Topic
- Acupuncture Treatment Research Studies
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Department of Science and Technology of Sichuan Province