Comparing Prophylactic Administration of Sulbactam/Ampicillin Versus Cefmetazole for Prevention of Perineal Wound Infection Following Abdominoperineal Resection for Rectal Cancer: A Multicenter Randomized Controlled Trial
The 4-day SBT/ABPC regimen significantly reduced the incidence of PWI after APR compared to the 1-day CMZ regimen. This simple approach to antibiotic selection may be beneficial for preventing PWI.
Authors
- Masanori Tokunaga (ORCID: https://orcid.org/0000-0002-3183-349X)
- Akitoshi Nankaku (ORCID: https://orcid.org/0000-0002-9947-9458)
- Noriko Iwata
- Hiroyuki Sato (ORCID: https://orcid.org/0000-0002-9507-9887)
- Hiroyuki Hazama
- Akihiro Hirakawa
- Yusuke Kinugasa (ORCID: https://orcid.org/0000-0002-7885-2276)
- Akio Shiomi (ORCID: https://orcid.org/0000-0001-5657-8686)
- Shinichi Yamauchi (ORCID: https://orcid.org/0000-0002-2360-5323)
- Hiroyasu Kagawa (ORCID: https://orcid.org/0000-0001-8741-8992)
- Taiki Masuda (ORCID: https://orcid.org/0000-0003-0191-5176)
- Shunsuke Kasai (ORCID: https://orcid.org/0000-0002-2497-5633)
- Shunichiro Kato
Institutions
- Tokyo Medical and Dental University (JP)
- Shizuoka Cancer Center (JP)
- Tsuchiura Kyodo General Hospital (JP)
- Shizuoka General Hospital (JP)
- Edogawa Hospital (JP)
- Musashino Red Cross Hospital (JP)
- The University of Tokyo (JP)
Publication Details
- Journal
- Annals of Gastroenterological Surgery
- Published
- 2025-10-26
- DOI
- https://doi.org/10.1002/ags3.70118
- Primary Topic
- Surgical site infection prevention
- Type
- article
- Field-Weighted Citation Impact
- 0.00